Supplementary publications presented by Mr J. M. Stagg for the degree of D.Sc.

Volume 01 | BRITISH POLAR YEAR EXPEDITION FORT RAE, N.W. CANADA 1932-33 VOLUME I | DISCUSSION OF RESULTSVolume 02 | BRITISH POLAR YEAR EXPEDITION FORT RAE, N.W. CANADA 1932-33 VOLUME II | TABLESVolume 03 | 01. Some General Characteristics of Aurora at Fort Rae N.W. Canada 1932-33 | 02. NUMERICAL CHARACTER FIGURES OF MAGNETIC DISTURBANCE IN RELATION TO GEOMAGNETIC LATITUDE | 03. .Aspects of the Current System Producing Magnetic Disturbance | 04. The Diurnal Variation of Magnetic Disturbance in High Latitudes | 05. On the Variability of the Quiet -Day Diurnal Magnetic Variation at Eskdalemuir and Greenwich. By S. CHAPMAN, F.R.S., AND J. M. STAGG. | 06. On the Variability of the Quiet -Day Diurnal Magnetic Variation. Part II. BY S. CHAPMAN, F.R.S., AND J. M. STAGG. | 07. On the Variability of the Quiet -Day Diurnal Magnetic Variation. Part II. BY S. CHAPMAN, F.R.S., AND J. M. STAGG. | 08. Hourly Character Figures of Magnetic Disturbance at Kew Observatory, Richmond 1913-23 | 09. The Time Interval BETWEEN Magnetic Disturbance AND Associated Sunspot Changes | 10. THE ABSOLUTE DAILY RANGE OF MAGNETIC DECLINATION AT KEW OBSERVATORY, RICHMOND, 1901 to 1910 | 11. On Magnetic Fluctuations and Sunspot Frequency: A Discussion based primarily on the daily ranges of Declination as recorded at Kew Observatory, Richmond, during the 67 years 1858-1924 | 12. The 27-Day Recurrence Interval in Magnetic Disturbance: An Examination made with the aid of hourly Character Figures

George Mathews and John McKee: Revolutionizing East Florida, Mobile, and Pensacola in 1812

It has become conventional to regard the East Florida revolution of 1812 as a singularly colorful and controversial episode in the history of the early republic. Its colorful aspects have lent themselves to the writing of fast-paced narratives that make for good reading because its organizers-United States government agents George Mathews and John McKee-brought to the performance of their duties roughly equal proportions of outright illegality, low intrigue, and not a little incompetence. The revolution they staged has always been controversial because it has been difficult to escape the conclusion that it embodied the desire of the administration of James Madison to enlarge the nation by actively subverting the Spanish regime in East Florida.1 It is now reasonably clear that the actions of Mathews and McKee in Florida and on the Gulf Coast between 1810 and 1812 departed far more from the policies of the administration than they fairly reflected them

The targeting of corticosteroids to inflamed tissues

In recent years, much interest has focused on the beneficial effects of administering potentially harmful therapeutic agents in drug carriers so as to reduce their toxic side effects. Rheumatoid arthritis is a chronic systemic disease with progressive destruction of the Joints and long term patient disability, Corticosteroids have been shown to retard the progression of Joint destruction but are limited in their use due to adverse side effects,This project, following the line of investigation started by other workers, was designed to study the use of microspheres to deliver corticosteroids to inflamed tissues by both the oral and intravenous routes. Hydrocortisone (HC)-loaded albumin microspheres were prepared by three different methods, by direct incorporation of HC within the particles, by indirect incorporation of HC by the enzymatic conversion of hydrocortisone-21-phosphate (H-21-P) to HC within the particles, and by the adsorption of HC onto the surface. HC was also loaded with PLA microspheres. The level of corticosteriod loading and in vitro release from microspheres was determined by HPLC analysis. A reversed-phase, ion-pairing HPLC method was developed to simultaneously measure both HC and H-21-P. The highest level of corticosteroid loading was achieved using the incorporation of H-21-P with enzymatic conversion to HC method. However, HPLC analysis showed only 5% of the incorporated steroid was HC. In vitro release rates of steroid from albumin microspheres showed >95% of incorporated steroid was released within 2 hours of dissolution. Increasing the protein:steroid ratio, and the temperature and duration of microsphere stabilization, had little effect on prolonging drug release. In vivo studies, using the carrageenan-induced rat hind-paw model of inflammation, indicated steroid-incorporated microspheres administered both orally and intraperitoneally were not therapeutically advantageous when compared to equivalent free steroid doses. The ability of orally and intravenously dosed [125I]~albumin microspheres (2.67 μm mean diameter) to accumulate in acutely and chronically inflamed tissues was investigated, The subcutaneous air-pouch was the model of inflammation used, with carrageenan as the inflammatory stimulus. Acute and chronic inflammation was shown to be consistently formed  in pouch tissues in terms of cell infiltration and fluid exudate formation in the pouch cavity. Albumin microspheres were shown to accumulate in the inflamed tissues and pouch fluids after both oral and intravenous administration. Preliminary, confirmatory studies using latex microspheres and quantitation by GPC analysis, also indicated microsphere accumulation in both acutely and chronically inflamed air-pouch tissues. tntl lUr"'poucbtis,sues; The results indicate the uptake and transfer of microspheres across the gastrointestinal tract into the circulation and their migration through disrupted endothelium and basement membranes at the inflamed sites. ,

Solvable Leibniz algebras with triangular nilradical

A classification exists for Lie algebras whose nilradical is the triangular Lie algebra $T(n)$. We extend this result to a classification of all solvable Leibniz algebras with nilradical $T(n)$. As an example we show the complete classification of all Leibniz algebras whose nilradical is $T(4)$.Comment: arXiv admin note: text overlap with arXiv:1307.844

A Frattini Theory for Leibniz Algebras

A Frattini theory for non-associative algebras was developed by Towers and results for particular classes of algebras have appeared in various articles. Especially plentiful are results on Lie algebras. It is the purpose of this paper to extend some of the Lie algebra results to Leibniz algebras